Wellcome Trust Sanger Institute

The Wellcome Trust Sanger Institute’s Public engagement team works with teachers, science education experts and the Institute’s scientists to develop teaching resources on genetics and genomics.

These tried and tested resources cover topics that relate to our genomics research and are relevant to the national curriculum and GCSE, AS and A-level science specifications for 14-19 year olds. The resources in this collection may be used during lessons, science clubs or as homework tasks and range from animations to paper and web-based activities that cover topics including:

• how DNA is sequenced
• the Human Genome Project
• genetics of cancer
• genetics of bacterial pathogens such as MRSA and Salmonella
• biology of malaria
• human variation in health and disease
• use of model organisms in genome research

The Wellcome Trust Sanger Institute is one of the world's leading genome centres. A key player in the Human Genome Project, the Sanger Institute is focused on understanding the role of genetics in health and disease by using the latest genomic technologies and techniques.

Resources

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Model Organisms: Zebra Fish

Produced by the Wellcome Trust Sanger Institute, in this activity students have to use their observational skills to identify and record the difference (phenotypic change) between two images, one wild type zebra fish and one mutant zebra fish.

To aid in their diagnosis of the phenotypic change, a glossary...

KRAS: Cancer Mutation Activity

These materials contain a range of activities where students use real genomic data from the Cancer Genome Project at the Wellcome Trust Sanger Institute to find mutations in a gene associated with pancreatic cancer. Students mark the locations of the mutations on a gene sequence banner and record the results on...

Genome Generation

A number of scenarios are presented to encourage debate around genome sequencing. All teaching materials are provided.

  • The interaction of genetic and environmental factors in influencing phenotype
  • Ethical implications of genetic screening

Curriculum links:

  • Sequencing...

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