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These resources have been reviewed and selected by STEM Learning’s team of education specialists for factual accuracy and relevance to teaching STEM subjects in UK schools.

Gel Electrophoresis of DNA

Produced by Science & Plants for Schools (SAPS), this activity enables students to look at the gel electrophoresis of DNA treated with restriction enzymes. It will help to develop a knowledge and understanding of the cutting of DNA with restriction enzymes.

In the experiment, a batch of DNA is digested by two different restriction enzymes. The fragments are separated by gel electrophoresis and the difference in patterns analysed.

The investigation is designed for students following a Scottish Highers course but it is equally useful for other post-16 courses in biology. It could also be adapted for younger secondary school students.

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