Semi-conservative replication images

A collection of images representing semi conservative DNA replication:

Illustration depicting semi-conservative DNA replication 1. Three generations of DNA are shown. After separation of the DNA double helix, two new complementary DNA strands are synthesised (indicated by a new colour). Complementary base pairing and hydrogen bonding results in formation of a new double helix.

Credit: Susan Lockhart, Wellcome Images

Illustration depicting semi-conservative DNA replication 2. A DNA double helix prior to replication is shown in the top left of the image. The sugar phosphate backbone and nucleotide bases are visible. Complementary base pairing of adenine with thymine (blue with green) and guanine with cytosine (red with yellow) is shown. During replication, a length of the double helix temporarily unwinds and separates into two strands. Free nucleotides bind by complementary base pairing to the recently exposed nucleotides on each strand which act as a template. Two new double helices are formed, each containing one original generation and one new generation strand of DNA. The sequence of base pairs in each double helix is identical to the original.

This resource is part of the Post 16 genetics and genomics collection.

Credit: Susan Lockhart, Wellcome Images