Stuff and Substance is a multimedia package developed by the Gatsby Science Enhancement Programme (SEP). It aims to address the difficulties many students have in understanding fundamental ideas in chemistry. The carefully constructed sequence of content in Stuff and Substance develops the concept of a substance...

This animation shows the major stages of subcloning. This is the process of breaking up fragments of DNA from BAC clones into smaller more manageable pieces for DNA sequencing. This process was very important during the Human Genome Project. Subcloning involves several standard molecular biology techniques...

These downloadable animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to develop the idea of chemical change as a change of substance.

These downloadable videos and animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to develop the idea of chemical change by showing that in some reactions substances decompose...

These downloadable videos and animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to develop the idea that some crystals incorporate water molecules within their structures....

These downloadable videos and animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to develop the idea of chemical change by showing reactions that take place spontaneously at...

These downloadable videos and animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to develop the idea of chemical change by showing reactions that takes place between substances...

These downloadable videos and animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to develop the idea of chemical change by showing a reaction that takes place on heating to a...

These downloadable animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to emphasize that a substance can be in any of the three states and there is nothing special about room...

From the Wellcome Trust, this animation shows how syphilis, a sexually transmitted bacterial disease (STD), can infect a person's lymph nodes. If this initial infection is not treated, the bacteria can spread to cause damage to the heart, aorta, brain, eyes and bones. In some cases, untreated syphilis can result in...

Published by the Wellcome Trust, the ‘Big Picture’ explores issues around biology and medicine.​

This resource includes...

These downloadable videos and animations are part of the multimedia package Stuff and Substance, developed by the Gatsby Science Enhancement Programme (SEP). They can be used to predict the possibility of the gas state with the particle model and understand that ‘gases...